Download scientific diagram | Mean (± sem) number of conditioned gaping reactions at test elicited by LiCl-paired saccharin solution among groups pretreated with OlGly or OlAla (ip). *p < 0.05; **p < 0.01 different from VEH from publication: Effect of oleoyl glycine and oleoyl alanine on lithium chloride induced nausea in rats and vomiting in shrews | Rationale The fatty acid amide oleoyl glycine (OlGly) and its more stable methylated form oleoyl alanine (OlAla) reduce naloxone-precipitated morphine withdrawal (MWD)-induced conditioned gaping (nausea) responses in rats. In addition, OlGly has been shown to reduce lithium | Vomiting, Alanine and Glycine | ResearchGate, the professional network for scientists.
Mean (±SEM) number of gapes elicited by LiCl-paired saccharin during
Mean ( ± S.E.M.) frequency of gaping responses expressed by Group
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Histograms for percentage reactions in test 1 (left, n = 6) and test 2
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Raphael MECHOULAM, Ph.D., Hebrew University of Jerusalem, Jerusalem, HUJI, Faculty of Medicine
A) Mean (+S.E.M.) frequency of gaping responses expressed by groups
Mean ( ± S.E.M.) frequency of gaping responses displayed by Group
a Mean (+SEM) reaction times for the test phase of Experiment 2. b Mean
Effect of oleoyl glycine and oleoyl alanine on lithium chloride induced nausea in rats and vomiting in shrews
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Raphael MECHOULAM, Ph.D., Hebrew University of Jerusalem, Jerusalem, HUJI, Faculty of Medicine